Neurontin fails bipolar med review-Fierce Pharma.
"Review the research on epilepsy meds, and what do you find? Neurontin (gabapentin), is no better than placebo for bipolar disorder, according to the Prescribing for Better Outcomes center at the University of North Carolina.
A bunch of "very poor quality articles," however, seemed to support a positive effect--and those articles were cited and re-cited in the scientific literature, creating an "echo chamber effect." Hearing it over and over, doctors were led to believe that Neurontin worked for bipolar patients, and prescribed it to lots and lots of them.
Ironically, the epilepsy-med review came courtesy of the 2004 Neurontin marketing settlement, under which Pfizer paid $430 million to settle off-label allegations. Some 94 percent of the drug's sales in 2002 were off-label, the government said at the time."
from --Fierce Pharma
Sunday, April 20, 2008
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6 comments:
http://dida.library.ucsf.edu/
thank you anon!
Thanks for this, Stephany. I have an upcoming post that will link to you and slightly elaborate on this.
tie it in w the anti depressant equates placebo story. i'm too tired to pull it all together
thank you for this stephany. raine had told me about neurontin also. i did some investigating when it was prescribed to rob, and i was skeptical myself. but he was doing so well on the neurontin and seroquel combo, i didn't want to mess with it. i think the neurontin actually did do something for his anxiety... perhaps nothing at all for the mood swings, dunno.
whatever works.
right now he's doing quite well with no meds or therapy (other than me, lol) at all.
i think it's great that he is doing so well, you are a great mom .
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