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Though the Defense Health Board recommended a review of the guidelines for non-FDA approved, off-label use of drugs, including SEROQUEL , a powerful neuroleptic designed for symptom relief for schizophrenia and psychosis, the military is going forward with the use of 25mg Seroquel for insomnia for use in active U.S. troops deployed overseas.
This is the definition of the Defense Health Board that advises the secretary of defense:
Defense Health Board is a Federal Advisory Committee to the Secretary of Defense
Providing independent scientific advice/recommendations on matters relating to operational programs, health policy development, health research programs, and requirements for the treatment and prevention of disease and injury, promotion of health and the delivery of health care to DoD beneficiaries
Mission
Independent authoritative advice to maximize the health, safety, and effectiveness of the United States Armed Forces.
Ut Omnes Viverent "That all might live"
Considering the side effects of the antipsychotic Seroquel, such as :
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); confusion; difficult or painful urination; fainting; fast, slow, or irregular heartbeat; fever, chills, or persistent sore throat; hallucinations; increased saliva production or drooling; increased sweating; memory loss; menstrual changes; muscle pain, stiffness, or weakness; new or worsening mental or mood changes (eg, aggressiveness, agitation, anxiety, depression, exaggerated feeling of well-being, hostility, impulsiveness, inability to sit still, irritability, panic attacks, restlessness); numbness, burning, or tingling; persistent, painful erection; red, swollen, blistered, or peeling skin; seizures; severe or prolonged dizziness, light-headedness, or headache; shortness of breath; suicidal thoughts or actions; swelling of the hands, legs, or feet; symptoms of high blood sugar (eg, increased thirst, hunger, or urination; unusual weakness); tremor; trouble concentrating, speaking, or swallowing; trouble sleeping; trouble walking or standing; uncontrolled muscle movements (eg, arm or leg movements, jerking or twisting, twitching of the face or tongue); vision changes.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); confusion; difficult or painful urination; fainting; fast, slow, or irregular heartbeat; fever, chills, or persistent sore throat; hallucinations; increased saliva production or drooling; increased sweating; memory loss; menstrual changes; muscle pain, stiffness, or weakness; new or worsening mental or mood changes (eg, aggressiveness, agitation, anxiety, depression, exaggerated feeling of well-being, hostility, impulsiveness, inability to sit still, irritability, panic attacks, restlessness); numbness, burning, or tingling; persistent, painful erection; red, swollen, blistered, or peeling skin; seizures; severe or prolonged dizziness, light-headedness, or headache; shortness of breath; suicidal thoughts or actions; swelling of the hands, legs, or feet; symptoms of high blood sugar (eg, increased thirst, hunger, or urination; unusual weakness); tremor; trouble concentrating, speaking, or swallowing; trouble sleeping; trouble walking or standing; uncontrolled muscle movements (eg, arm or leg movements, jerking or twisting, twitching of the face or tongue); vision changes.
Including box warnings for QT Prolongation (risk of sudden death /cardiac arrest),diabetes,pancreatitus, blood clots......
Image courtesy of U.S. Army.
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